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       PAT-ChIP references:

 

  • "Pathology tissue-chromatin immunoprecipitation, coupled with high-throughput sequencing, allows the epigenetic profiling of patient samples" - (2010) - Proc Natl Acad Sci USA  

  • "Chromatin immunoprecipitation and high-throughput sequencing from paraffin-embedded pathology tissue" - (2011) - Nature Protocols 

  • "PAT-ChIP coupled with laser microdissection allows the study of chromatin in selected cell populations from paraffin-embedded patient samples" - (2014) - Epigenetics & Chromatin

  • "Epigenomic profiling of archived FFPE tissues by enhanced PAT-ChIP (EPAT-ChIP) technology" - (2018) - Clinical Epigenetics

 

PAT-ChIP technology was developed by the Molecular Pathology Lab. "PaoLa" 

in collaboration with the European Institute of Oncology (Milan - Italy)

PAT-ChIP procedure was developed to allow epigenetic studies using FFPE-tissue samples.

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